07-15-2022

Both Miaomiao and Yin were selected to give oral presentations in 2022 Gordon Proteoglycan conference! They have both done excellent jobs presenting and really showcased the diverse subjects we study in the lab!

07-14-2022

Our lab is awarded with a new 5-year R01 grant from NIDCR to study the role of Heparan sulfate–cathepsin K interaction in bone remodeling !

07-02-2022

Miaomiao scored an excellent priority score of 23 in her resubmission of NIDCR R03 award for Young Investigators. Really proud of her and hopefully this award will help she secure an independent faculty position!  

02-01-2022

Miaomiao's RAGE paper is officially accepted by eLife today! This is our third paper on RAGE since 2011. By using a novel RAGE knock-in strain and an mAb that specifically target the HS-binding site, we demonstrated that HS-induced oligomerization is essential for RAGE signaling in vivo

08-04-2021

Xiaoxiao successfully defended her thesis today, becoming the first PhD out of Xu lab. Congratulations!

01-20-2021

Xiaoxiao's cystatin C paper was officially accepted by Communication Biology today! Another prime example of the structural diversity of HS-binding site. 

07-08-2020

Miaomiao's OPG knockin mice paper appeared online today on PNAS website! This is our third paper on OPG and first knock-in animal with impaired HS-binding site. 

06-18-2020

We have completed moving the lab to a new space in Biomedical Research Building. A refreshing change after a long dormancy during COVID19!

06-02-2020

We were awarded $90,000 by Buffalo Accelerator Funds to develop our anti-RAGE mAb for treatment of inflammatory diseases !