Ding Xu, PhD

Associate Professor

Dr. Xu has been studying heparan sulfate his whole scientific career. He was highly fortunate to be mentored by two leading experts in heparan sulfate biology. With Dr. Jian Liu at UNC Chapel Hill, he studied biosynthetic enzymes of heparan sulfate and became an expert in HS structure, HS biosynthesis, protein expression and purification, and structural biology. With Dr. Jeff Esko at UCSD, he studied the physiological roles of heparan sulfate in vascular biology, inflammation and infection, during which time he became an expert in cell biology and animal models of human diseases. In 2014, Dr. Xu moved to the University at Buffalo to established his own lab with a new direction to study the role of HS in bone remodeling. Benefitted from his diverse training background, the type of study his lab is conducting is highly multidisciplinary, often spans structural biology, biochemistry, cell biology, genetically modified murine models and development of therapeutics.  

Education

1995 - 1999

Central China Normal University

BS in Biochemistry

2002 - 2006

University of North Carolina at Chapel Hill

School of Pharmacy

PhD in Pharmaceutical Sciences

2007 - 2011

University of California, San Diego

Department of Cellular and Molecular Medicine

School of Medicine

Postdoctoral fellow

2011 - 2014

University of California, San Diego

Department of Cellular and Molecular Medicine

School of Medicine

Staff Scientist

2014 - 2019

University at Buffalo, SUNY

Department of Oral Biology

School of Dental Medicine

Assistant professor

Email: dingxu@buffalo.edu

Tel: 716-829-3509

Education

Miaomiao Li, PhD

Research Scientist

2005 - 2009

Shandong University of Traditional Chinese Medicine

BS in Pharmacy

2009 - 2015

Ocean University of China

School of Pharmacy

PhD in Pharmaceutical Sciences

Projects:

HS–OPG interactions in osteoclastogenesis

HS–RAGE interactions in inflammation and bone remodeling

2015 - 2020

University at Buffalo

Department of Oral Biology

Postdoctoral Scholar

Xiaoxiao Zhang

PhD student (2016)

Projects:

Role of HS in regulating osteoclast activity

Structural characterization of novel HS-binding proteins

Education

2006 - 2012

Shanghai Jiao Tong University

School of Medicine &Stomatology

BS in Stomatology

2012 - 2014

Shanghai Jiao Tong University

School of Medicine &Stomatology

MS in Oral and Maxillofacial Implantology

2014 - 2016

Shanghai Ninth People’s Hospital

Dental resident

Chih-Yean Ong

PhD student (2018)

Education

2009 - 2013

International Medical University, Malaysia

BS in Pharmaceutical Chemistry

2013 - 2018

Quality control management in various pharmaceutical companies in Malaysia and Singapore. 

Projects:

Role of HS in regulating osteoblast differentiation

Development of anti-RAGE mAb

Yin Luo

PhD student (2019)

Education

Projects:

Role of HS in regulating osteoblast activity

Role of HS in regulating osteoclast activity

2011 - 2016

Central South University

Xiangya School of Stomatology

BS in Stomatology

2016 - 2019

Central South University

Xiangya School of Stomatology

MS in Endodontics